DNA-TECH Pre-Natal screening service: fluorescent-PCR
Chromosomes carry the genetic instructions necessary for life. Humans have 46 chromosomes and inherit 23 from each parent. DNA-TECH Limited is the only private laboratory to offer fluorescent-PCR screening in Asia. Fluorescent-PCR allows rapid screening for fetal abnormalities. DNA-TECH focuses on screening 5 chromosome defects that account for over 95% of fetal chromosomal aneuploidy
We focus on detecting the following conditions:
• Trisomy 21 V Down's syndrome
• Trisomy 18 V Edward's syndrome
• Trisomy 13 V Patau's syndrome
• X-aneuploidy and Y-aneuploidy
How's the chromosomal aneuploidy test carried out ?
After consultation, your OG doctor will perform an amniocentesis. Amniocentesis should be performed after 16 weeks gestation to collect fetal cells for testing. Samples obtained will be sent for screening to our laboratory. Karyotyping and fluorescent-PCR are two common screening methods.
| Karyotyping |
fluorescent-PCR |
| 10 working days
or more |
1 working day |
| Screen for all
chromosomes |
Screen for chromosome 13, 18, 21, X, Y only ;
Over 95% of fetal chromosomal aneuploidy |
Advantages of fluorescent-PCR
 Karyotyping normally takes 2-3 weeks to determine the genetic health of the fetus. This can be a very stressful time for parents, as they may need to make very important decisions based on the test results. Fluorescent-PCR is a new technology that can screen the chromosomes causing 95% of fetal chromosomal aneuploidy within one day. This helps to relieve the stress and allows extra time for parents to make important decisions. |
